A bitter flavor for health

The ABCs of Biotech for Christians - Eighteenth in a series - Q is for Quinine

Quinine holds a special place in science history as the first chemical compound ever used successfully against infectious disease. During the American Civil War, its importance in treating malaria led to the first large-scale drug manufacturing operations and the first federal drug-testing program.

Quinine is derived from the bark of the Cinchona tree, an evergreen native to the Andes tropical forests, by isolating it from the bark through a process that also crystalizes its alkaloids— which are naturally occurring organic compounds with a nitrogen base. Quinine has healed the sick from kings to the poorest infant, and enabled armies over the centuries to maintain troop vigor and achieve military conquests.

In use since the 1600s, many chemists starting in the 18th century studied quinine to understand its properties, and worked to determine how it might be reinvented in a laboratory for mass production as a pharmaceutical. Though they figured out its molecular structure, and ultimately, in the 1940s, how to synthesize it from coal tar, the vast research led to better chemical discoveries for malaria treatment, though quinine still is used.

Today, biotechnology plays a large role in synthesizing and producing alkaloids for commercial use on an industrial scale. The discoveries of biotech and molecular biology make it convenient to transfer and propagate genes in plant cells, among other processes, to commercially produce alkaloid related drugs.

An aside: This webpage explains how to make a transgenic plant.

In current clinical trials, quinine is being studied “To investigate the effect of oral sham feeding and intragastric delivery of a bitter tastant on food intake.” In other words, this is research to determine whether quinine could assist obese people to eat less. It is also under study to discover how it interacts or reacts with other compounds and medicines for more effective treatments for a range of illnesses.

Despite the wonderful progress in medicinals, in 2016, there were an estimated 216 million cases of malaria in 91 countries, an increase of 5 million cases over 2015, and malaria deaths reached 445,000 in 2016, a similar number (446,000) to 2015. In 2016, nearly half the world’s population was at risk of malaria, and the latest World Malaria Report (Nov 2017) stated there were 216 million cases in 2016, up from 211 million in 2015.

There is no vaccine against malaria, though some progress in vaccines has been reported.

The story of Elisha and the pottage made for the prophets’ families comes to mind. There was a famine in the area so the stew was made with whatever was found in the field including wild gourds. Upon eating it, the prophets’ sons cried out, “There is death in the pot!” (2Ki 4:40) So Elisha cast some meal or flour into the pot, and remedied the poisoned stew.

I am not likening quinine to the meal that was cast into the stew. Then as now, the flour is symbolic of the bread of life, Christ, who must assist to bring health back, and with His help, biotechnology can find new ways to heal. It is true, though, that Christ is a bitter flavor to many.

On the verge of becoming... God?

Eighth in the PE Series, Reviewing Chapter Seven

Want to see a video of pigs that glow in the dark? Click. "The pigs are transgenic, created by adding genetic material from jellyfish into a normal pig embryo." [Original report] How do the pigs feel about this?

Another example of genetic tampering is the creation of human-spider goats whose milk can be treated to produce spider silk.

This and lots more information was shared in Chapter Seven of Pandemonium's Engine, Man Becoming His Own God? by Douglas Hamp, who asks: "Should planetary supremacy entitle the human race to inflict inhumane, unnatural acts upon any sub-intellectual life-form for financial gain?" Learn more about Douglas and his presentations on his blogsite.

In the process of following leads given in his chapter, I came across some interesting quotations:
"The most powerful code is no longer a string of 1s and 0s." - "DNA Space. The Geography of the Genome," WIRED, June 2003
Definition of Life Sciences: "The science of using living organisms and/or their constituent parts to replace or augment products or processes. Life Science products include fuels, chemicals, lubricants, pharmaceuticals, nutraceuticals, clothing, plastics and building materials." from http://www.biotechonomy.com
From the arstechnica.com website, quoted by Hamp on p 240:

Humanity is on the verge of becoming a new and utterly unique species, which [Juan Enriquez, Biotechonomy CEO] dubs Homo Evolutis. What makes this species so unique is that it "takes direct and deliberate control over the evolution of the species." Calling it the "ultimate reboot," he points to the conflux of DNA manipulation and therapy, tissue generation, and robotics as making this great leap possible.

We are already in the midst of minor improvements to the human body and mind; Enriquez gave examples of growing new tissues for successful transplant, programmable cells, and augmenting our abilities through robotics. As this trend accelerates, more and more aspects of the human experience, of the human life, will be capable of scientific manipulation. While some improvement may come post-birth, our understanding of DNA and biology may lead to something much bigger.

Hamp points out that chimeras are being invented. A chimera is a hybrid creature that is part human, part animal. Though many genomic discoveries in the biosciences are marvelous and helpful, others are dark and should never be permitted. He ends his chapter with this thought:

Man now possesses the power, via transgenics and transhumanism, to direct his own evolution. Tinkering with his code at the genetic level (DNA) is not only possible, but is currently being done. Strange animal hybrids are being made in the laboratory and even humans with animals are being experimented with; man is certainly open to improving himself in any way possible… Could the science of transhumanism and transgenics play a role in the rise of the Antichrist and the Mark of the Beast? Could technology allow Satan to create one from his own seed as Genesis 3:15 predicts? Satan's end game has been in the making now for many decades and will very soon be put into play.

That is a concept or definition of "seed" that I had not thought of. Several of the PE authors understand demonic "seed" as transhuman types of creatures, those not fully human but genetically altered. Yet, you do not need to have your DNA changed to belong to Satan and be his child. Just turn your back on God. You will be Satan's seed.

Angel fish
Public Domain, Link

...and every living creature that moveth, which the waters brought forth abundantly, after their kind, and every winged fowl after his kind ... the living creature after his kind, cattle, and creeping thing, and beast of the earth after his kind ...the beast of the earth after his kind, and cattle after their kind, and every thing that creepeth upon the earth after his kind: and God saw that it was good. -Genesis 1


A SistersSite eBook

Flesh and Bone and The Protestant Conscience is an e-book on Amazon.com. It is 99¢ and in the Amazon lending library as well. It is also available here in PDF format. The book description follows.

Would you let your conscience be your guide?

Does God care if the skin and bone of the dead are passed along to the living for medical uses? Is organ donation OK with God? Should you sign a Living Will?

Did you know that dead organ donors are often anesthetized before their organs are removed? Do you know the current definition of death? The conscience cannot function without facts.

As we ponder the ethics of in vitro fertilization, stem cell research and man-made chimeras, our thoughts trail off. How then should we live? (Ez 33:10)

How should a Christian think about euthanasia by starvation when doctors and the state attorney general all agree it is time to withhold feeding from a brain injured patient? Some things are family matters, but someday it may be our family.

Here is a small book to help you think about whether you want to sign your driver's license, donate a kidney, cremate your loved one, and many other practical questions that may arise in the course of your healthcare decisions or watch over others.

It offers a special focus on the doctrine of the Resurrection that is related to such decisions. Sunday School classes and Bible Study groups could use this book to facilitate discussion about the issues covered.